In contrast, the concordance of benchmarking results for all outcomes, including mortality, in the SURPASS-CVOT emulation study comparing tirzepatide to dulaglutide provided support for the validity of evaluating these outcomes in expanded study populations
GLP-1 receptor agonist drugs (called GLP-1s for short) like semaglutide work by mimicking this hormone, increasing insulin release (which helps control diabetes), signaling your brain that you're full, and slowing digestion
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Epub 2022 Feb 20
Francesca Mangialasche, Karolinska Institutet, Center for Alzheimer Research, Sweden